Antihypertensive drugs can cause diabetes?
Question
Antihypertensive drugs can cause diabetes?
Answer
Supporting Organizations: Shanghai Hypertension Institute of Shanghai Second Medical University Ruijin Hospital Hypertension Division鍧愬爞Experts: Chen Guo line early鍐'鐝峵hrifty little hot鑾夋潨question; as antihypertensive agents, diuretics cause diabetes? Guo鍐'鐝? A caller hypertensive patients consulting, he served a long-term Zhenju Jiangyapian, sometimes taking indapamide (that is, made quot;life than the Mountainquot;, the import of quot;reminder from satisfiedquot;). Recently found that hyperglycemia was diagnosed with diabetes. He asked whether the long-term use of diuretics because he suffers from diabetes. In fact, at present, many large-scale studies have evidence of globalIndeed, diuretics are the most valuable one of antihypertensive drugs. As a result of the past 20 years, diuretics for blood pressure will gradually reduce the dose, for example: the last century, 70 to 80 years, Hydrochlorothiazide dosage urinary thiophene 50 to 100 mg has been reduced to 12.5 mg / day or so. Therefore, Thiazide diuretics increase serum lipids, blood glucose, uric acid and reduce the side effects of potassium and indapamide reduced serum potassium, elevated uric acid has significantly reduced side effects. The contrary, has been found that low-dose diuretics in hypertensive patients can reduce left ventricular mass index, but also to reduce the recurrence of stroke. In particular, indapamide, or will notHyperlipidemia, and patients with diabetic nephropathy can reduce the proteinuria, the protection of the kidney. 1031 hypertensive patients had fasting blood glucose checks, not taking indapamide increase after the glucose. Therefore, it is commonly used in Zhenju Jiangya Tablet, three times a day, a piece of, Hydrochlorothiazide urine volume thiophene 15 mg / day, and quot;life than the mountains,quot; 1.25 ~ 2.5 mg / day dose does not cause diabetes . Diabetes is a multifactorial disease, the patient even if the above do not take diuretics blood pressure, diabetes also can occur. Q: What kind of drugs can lower systolic blood pressure drop? Guo鍐'鐝? aMembers suffering from high blood pressure in elderly hypertensive patients with more than ten years, the recent discovery of blood pressure in 140 ~ 150 mm Hg / 70 to 80 cents between the fluctuations绫宠础column, I heard that pulse pressure (difference between systolic and diastolic blood pressure) the greater the more dangerous it is, so a bit nervous Callers asked about which drugs should be taken to prevent the pulse pressure to continue to increase. High blood pressure early, as the ascending aorta better flexibility, increased peripheral vascular resistance, often result in diastolic blood pressure ( quot;lowquot;) was increased. When the long period of time when high blood pressure, impaired endothelial function, decreased flexibility, large artery, so that elastic buffer force to reduce, when systolic blood pressure ( quot;high pressurequot;) increased, but diastolic blood pressure instead of under theDown. This is increasing the burden on the heart, an increase of the possibility of cardiac events. Therefore, the greater the pulse pressure on blood vessels more rigid. Research confirmed that the use of converting enzyme inhibitors (such as Acertil), AII receptor antagonists (such as losartan), calcium antagonists (such as Norvasc) and diuretics may be increased in the early hypertensive vascular elasticity. In addition, nitrates (such as the new Ya-dan NOx) reduced systolic blood pressure greater than the option of lowering diastolic blood pressure. Therefore, when the patient started to become larger pulse pressure should be on time, under the guidance of the doctors taking the above-mentioned antihypertensive agents. Q: long-acting antihypertensive drug prices, how to take short-acting to reduce the fluctuations in blood pressure?Chen line: long-acting antihypertensive agents because of their chemical structure or the production process because of the elimination in the human body or the release of the slow time to reduce the number of medication, but also relatively stable blood pressure control purposes. However, the long-term high blood pressure drug prices, short-acting antihypertensive drugs relatively inexpensive, such as in compound hypotensive tablet, one day after taking repeated (three or four times daily medication), high blood pressure in some patients can better to lower blood pressure. If a mild to moderate high blood pressure, not associated with other diseases, they can take short-acting antihypertensive agents, but to remember to take three times a day (early, middle and late) in this way can be through an increase in medicationTo reduce the number of blood pressure fluctuations. Q: high blood pressure in elderly patients often feel dizzy, how should I do? Chen line: high blood pressure dizziness is often about the symptoms of patients, especially the elderly. Generally considered from the following, first, to know their blood pressure levels. Not enough to make taking blood pressure medicine high blood pressure, or excessive use of antihypertensive drugs to make blood pressure is too low (especially the elderly to get up when the station a long time), there are dizziness, requires a doctor based on your blood pressure further adjustment of antihypertensive drug. Second, whether or not accompanied by other diseases or symptoms. Such as cervical spondylosis, often dizziness, vertigo accompanied by words such as unclear or the side ofLimb numbness or weakness, need time, need to do further checks. Therefore, when high blood pressure with dizziness, do not easily add to or reduce the blood pressure medicine, do not blindly take other drugs, doctors should be asked to deal with. Q: Occasionally, the hospital or clinic measured blood pressure and blood pressure What is the difference between self-rated? DU Jian: blood pressure measurement often influenced by many factors, such as temperature, environment, emotions, activity status and the methods of pressure. Casual blood pressure clinic is the clinical standard method of diagnosis of high blood pressure, by health care professionals in the standard conditions of measurement in accordance with uniform standards. Blood pressure measurement, the measured rest at least 5 to 10 minutes,Check seat, bare right arm, palm upward骞充几, elbows at the same level as the heart. Each measurement can be repeated 2 or 3 times, each time blood pressure values (diastolic or both systolic blood pressure) difference between the lt;5 mm Hg, the average reading choice. Self-test blood pressure is measured at home or other environment to their own blood pressure measurement, the daily life of the state can provide valuable information on the blood pressure. In general, patients in the hospital or clinic blood pressure measurement, the hospital will be the environment, medical staff have a conditioned reflex, causing stress and anxiety, when the measured value will be high blood pressure, also known as 銆斻'?white coat hypertension . Therefore, the self-test blood pressure moreCan reflect the true blood pressure level, in the evaluation of antihypertensive effect, improve treatment compliance and to enhance the treatment of active participation of the unique advantages. Self-test blood pressure blood pressure levels in the evaluation of antihypertensive treatment and guidance has become the casual blood pressure clinics are an important supplement. Q: the installation of pacemaker patients in the electronic blood pressure monitor will not affect the outcome? Pacemaker interference by electromagnetic waves, mainly from the hospital environment or special venues, such as the construction site. Everyday life mobile phones and electronic components to monitor the use of devices increasing, it can interfere with pacemaker function. But generally too near the phone or electronic monitors or prolonged useWhen there will be interference. Usually occurs, such as cell phones interfere with pacemakers by mobile phones within 10 centimeters. Electronic blood pressure monitor blood pressure measurement when the magnetic field generated by small, weak intensity, when the pressure is not near as long as the pacemaker, the blood pressure of the pacemaker will not interfere with the basic. Therefore, the installation of pacemaker patients with electronic blood pressure monitor is safe. Q: As early as high blood pressure patients will be able to exercise it? DU Jian: appropriate physical activity on patients with hypertension have the benefits of exercise are also considered a kind of early. However, due to a clear morning after a high blood pressure, especially in cold temperatures will increase the blood vessels to contract, the day before taking the role of antihypertensive drugsAre also going down this time, the importance of timely medication to lower blood pressure in the early morning peak, so that the level of blood pressure at a relatively stable state in order to reduce the cardio-and cerebro-vascular disease complications. The best medication, such as after a period of time, such as efficacy of antihypertensive agents have started to go out after training. Patients with hypertension if antihypertensive agents against the early morning exercise on the go, especially in the cold winter, it is possible cardiovascular and cerebrovascular accidents. Q: It has already been treated with antihypertensive agents, but the early morning blood pressure is still high, how should I do? DU Jian: the early morning blood pressure is a very common phenomenon. The majority of hypertensive patients awake in the morning peak of blood pressure after 2 ~ 4 hours, even if already openBlood pressure before treatment, this situation may still exist, which may be related to drug efficacy and the duration of the effect. At this time, under the guidance of the doctors can take the time to peak early to blood pressure before medication as soon as possible after we wake up, and under the guidance of doctors to choose the appropriate length of a long-term effect of drug or drug combination can improve the blood pressure fluctuations in order to achieve a smooth 24-hour step-down purposes. (Editor: Wang Hai-e)
Antihypertensive drugs can cause diabetes?
Answer
Supporting Organizations: Shanghai Hypertension Institute of Shanghai Second Medical University Ruijin Hospital Hypertension Division鍧愬爞Experts: Chen Guo line early鍐'鐝峵hrifty little hot鑾夋潨question; as antihypertensive agents, diuretics cause diabetes? Guo鍐'鐝? A caller hypertensive patients consulting, he served a long-term Zhenju Jiangyapian, sometimes taking indapamide (that is, made quot;life than the Mountainquot;, the import of quot;reminder from satisfiedquot;). Recently found that hyperglycemia was diagnosed with diabetes. He asked whether the long-term use of diuretics because he suffers from diabetes. In fact, at present, many large-scale studies have evidence of globalIndeed, diuretics are the most valuable one of antihypertensive drugs. As a result of the past 20 years, diuretics for blood pressure will gradually reduce the dose, for example: the last century, 70 to 80 years, Hydrochlorothiazide dosage urinary thiophene 50 to 100 mg has been reduced to 12.5 mg / day or so. Therefore, Thiazide diuretics increase serum lipids, blood glucose, uric acid and reduce the side effects of potassium and indapamide reduced serum potassium, elevated uric acid has significantly reduced side effects. The contrary, has been found that low-dose diuretics in hypertensive patients can reduce left ventricular mass index, but also to reduce the recurrence of stroke. In particular, indapamide, or will notHyperlipidemia, and patients with diabetic nephropathy can reduce the proteinuria, the protection of the kidney. 1031 hypertensive patients had fasting blood glucose checks, not taking indapamide increase after the glucose. Therefore, it is commonly used in Zhenju Jiangya Tablet, three times a day, a piece of, Hydrochlorothiazide urine volume thiophene 15 mg / day, and quot;life than the mountains,quot; 1.25 ~ 2.5 mg / day dose does not cause diabetes . Diabetes is a multifactorial disease, the patient even if the above do not take diuretics blood pressure, diabetes also can occur. Q: What kind of drugs can lower systolic blood pressure drop? Guo鍐'鐝? aMembers suffering from high blood pressure in elderly hypertensive patients with more than ten years, the recent discovery of blood pressure in 140 ~ 150 mm Hg / 70 to 80 cents between the fluctuations绫宠础column, I heard that pulse pressure (difference between systolic and diastolic blood pressure) the greater the more dangerous it is, so a bit nervous Callers asked about which drugs should be taken to prevent the pulse pressure to continue to increase. High blood pressure early, as the ascending aorta better flexibility, increased peripheral vascular resistance, often result in diastolic blood pressure ( quot;lowquot;) was increased. When the long period of time when high blood pressure, impaired endothelial function, decreased flexibility, large artery, so that elastic buffer force to reduce, when systolic blood pressure ( quot;high pressurequot;) increased, but diastolic blood pressure instead of under theDown. This is increasing the burden on the heart, an increase of the possibility of cardiac events. Therefore, the greater the pulse pressure on blood vessels more rigid. Research confirmed that the use of converting enzyme inhibitors (such as Acertil), AII receptor antagonists (such as losartan), calcium antagonists (such as Norvasc) and diuretics may be increased in the early hypertensive vascular elasticity. In addition, nitrates (such as the new Ya-dan NOx) reduced systolic blood pressure greater than the option of lowering diastolic blood pressure. Therefore, when the patient started to become larger pulse pressure should be on time, under the guidance of the doctors taking the above-mentioned antihypertensive agents. Q: long-acting antihypertensive drug prices, how to take short-acting to reduce the fluctuations in blood pressure?Chen line: long-acting antihypertensive agents because of their chemical structure or the production process because of the elimination in the human body or the release of the slow time to reduce the number of medication, but also relatively stable blood pressure control purposes. However, the long-term high blood pressure drug prices, short-acting antihypertensive drugs relatively inexpensive, such as in compound hypotensive tablet, one day after taking repeated (three or four times daily medication), high blood pressure in some patients can better to lower blood pressure. If a mild to moderate high blood pressure, not associated with other diseases, they can take short-acting antihypertensive agents, but to remember to take three times a day (early, middle and late) in this way can be through an increase in medicationTo reduce the number of blood pressure fluctuations. Q: high blood pressure in elderly patients often feel dizzy, how should I do? Chen line: high blood pressure dizziness is often about the symptoms of patients, especially the elderly. Generally considered from the following, first, to know their blood pressure levels. Not enough to make taking blood pressure medicine high blood pressure, or excessive use of antihypertensive drugs to make blood pressure is too low (especially the elderly to get up when the station a long time), there are dizziness, requires a doctor based on your blood pressure further adjustment of antihypertensive drug. Second, whether or not accompanied by other diseases or symptoms. Such as cervical spondylosis, often dizziness, vertigo accompanied by words such as unclear or the side ofLimb numbness or weakness, need time, need to do further checks. Therefore, when high blood pressure with dizziness, do not easily add to or reduce the blood pressure medicine, do not blindly take other drugs, doctors should be asked to deal with. Q: Occasionally, the hospital or clinic measured blood pressure and blood pressure What is the difference between self-rated? DU Jian: blood pressure measurement often influenced by many factors, such as temperature, environment, emotions, activity status and the methods of pressure. Casual blood pressure clinic is the clinical standard method of diagnosis of high blood pressure, by health care professionals in the standard conditions of measurement in accordance with uniform standards. Blood pressure measurement, the measured rest at least 5 to 10 minutes,Check seat, bare right arm, palm upward骞充几, elbows at the same level as the heart. Each measurement can be repeated 2 or 3 times, each time blood pressure values (diastolic or both systolic blood pressure) difference between the lt;5 mm Hg, the average reading choice. Self-test blood pressure is measured at home or other environment to their own blood pressure measurement, the daily life of the state can provide valuable information on the blood pressure. In general, patients in the hospital or clinic blood pressure measurement, the hospital will be the environment, medical staff have a conditioned reflex, causing stress and anxiety, when the measured value will be high blood pressure, also known as 銆斻'?white coat hypertension . Therefore, the self-test blood pressure moreCan reflect the true blood pressure level, in the evaluation of antihypertensive effect, improve treatment compliance and to enhance the treatment of active participation of the unique advantages. Self-test blood pressure blood pressure levels in the evaluation of antihypertensive treatment and guidance has become the casual blood pressure clinics are an important supplement. Q: the installation of pacemaker patients in the electronic blood pressure monitor will not affect the outcome? Pacemaker interference by electromagnetic waves, mainly from the hospital environment or special venues, such as the construction site. Everyday life mobile phones and electronic components to monitor the use of devices increasing, it can interfere with pacemaker function. But generally too near the phone or electronic monitors or prolonged useWhen there will be interference. Usually occurs, such as cell phones interfere with pacemakers by mobile phones within 10 centimeters. Electronic blood pressure monitor blood pressure measurement when the magnetic field generated by small, weak intensity, when the pressure is not near as long as the pacemaker, the blood pressure of the pacemaker will not interfere with the basic. Therefore, the installation of pacemaker patients with electronic blood pressure monitor is safe. Q: As early as high blood pressure patients will be able to exercise it? DU Jian: appropriate physical activity on patients with hypertension have the benefits of exercise are also considered a kind of early. However, due to a clear morning after a high blood pressure, especially in cold temperatures will increase the blood vessels to contract, the day before taking the role of antihypertensive drugsAre also going down this time, the importance of timely medication to lower blood pressure in the early morning peak, so that the level of blood pressure at a relatively stable state in order to reduce the cardio-and cerebro-vascular disease complications. The best medication, such as after a period of time, such as efficacy of antihypertensive agents have started to go out after training. Patients with hypertension if antihypertensive agents against the early morning exercise on the go, especially in the cold winter, it is possible cardiovascular and cerebrovascular accidents. Q: It has already been treated with antihypertensive agents, but the early morning blood pressure is still high, how should I do? DU Jian: the early morning blood pressure is a very common phenomenon. The majority of hypertensive patients awake in the morning peak of blood pressure after 2 ~ 4 hours, even if already openBlood pressure before treatment, this situation may still exist, which may be related to drug efficacy and the duration of the effect. At this time, under the guidance of the doctors can take the time to peak early to blood pressure before medication as soon as possible after we wake up, and under the guidance of doctors to choose the appropriate length of a long-term effect of drug or drug combination can improve the blood pressure fluctuations in order to achieve a smooth 24-hour step-down purposes. (Editor: Wang Hai-e)